rs1041981

A SNP in the LOC100287329 gene on chromosome 6. Its most notable genotype is A;A: Higher myocardial infarction risk

Gene
LOC100287329
Location
Chr 631,573,007 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
40%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadHigher myocardial infarction riskWorth knowing · 2.018% of people
  2. C;CNot ratednormalTypical · 0.035% of people

On SNPedia: (A;A), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 18% C;C 35%
  • European ancestry (Utah)A;A 7% C;C 40%
  • Han Chinese (Beijing)A;A 22% C;C 29%
  • Japanese (Tokyo)A;A 19% C;C 36%
  • Yoruba (Nigeria)A;A 25% C;C 27%
  • African ancestry (Southwest US)A;A 28% C;C 28%
  • Chinese (Denver)A;A 15% C;C 19%
  • Gujarati IndianA;A 7% C;C 61%
  • Luhya (Kenya)A;A 31% C;C 20%
  • Mexican ancestry (Los Angeles)A;A 4% C;C 51%
  • Maasai (Kenya)A;A 34% C;C 17%
  • TuscanA;A 6% C;C 51%

Conditions, medicines and genes

Other LOC100287329 SNPs

All LOC100287329 SNPs

Notes

From SNPedia

Notes

827 males and 709 females, 606 subjects without cancer and 930 subjects with various cancers *rs1041981(A;C) (C804A, T60N) associated with lung cancer (CA + AA: CC, adjusted OR = 0.60, 95% CI = 0.37 - 0.97), in males but not in females

Source and license

Adapted from rs1041981 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.