rs2236225(G;G)

Common/normal

Magnitude
0.0Typical
Repute
Good
Frequency
46%Average of 11 populations
On SNPedia
rs2236225(C;C)Minus strand
Gene
MTHFD1

Frequency

Share of people with G;G in each HapMap population.

  • Chinese (Denver)65%
  • Yoruba (Nigeria)65%
  • Luhya (Kenya)60%
  • Han Chinese (Beijing)60%
  • African ancestry (Southwest US)58%
  • Japanese (Tokyo)53%
  • Tuscan36%
  • European ancestry (Utah)35%
  • Maasai (Kenya)34%
  • Gujarati Indian27%
  • Mexican ancestry (Los Angeles)17%

Other genotypes of rs2236225

  1. A;GBadPossible increased risk of birth defectsMinor · 1.343% of people
  2. A;AMost notableBadSlightly (~1.5x) higher risk for Caucasian mothers to give birth to NTD childrenMinor · 1.511% of people

All about rs2236225

Source and license

Adapted from rs2236225(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.