rs2241715
A SNP in the TGFB1 gene on chromosome 19. Its most notable genotype is A;A: common in clinvar
- Gene
- TGFB1
- Location
- Chr 1941,350,981 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 37%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2241715 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 17%
- European ancestry (Utah)A;A 11%
- Han Chinese (Beijing)A;A 25%
- Japanese (Tokyo)A;A 21%
- Yoruba (Nigeria)A;A 12%
- African ancestry (Southwest US)A;A 7%
- Chinese (Denver)A;A 38%
- Gujarati IndianA;A 18%
- Luhya (Kenya)A;A 9%
- Mexican ancestry (Los Angeles)A;A 14%
- Maasai (Kenya)A;A 9%
- TuscanA;A 20%
Related
Other TGFB1 SNPs
- rs1800469G;Glower TGF-β1 levels, higher risk for COPD?Minor
- rs1800470A;GNo summary available.Typical
- rs1800471C;Ccommon in clinvarTypical
- rs1800472G;Gcommon on affy axiom dataTypical
- rs1982073G;Grisk genotype for several disordersTypical
- rs4803455C;Ccommon in clinvarTypical
- rs8110090A;Acommon in complete genomicsTypical
- rs8179181G;Gcommon in clinvarTypical
Notes
From SNPedia
Notes
{{PMID Auto |PMID=19258388 |Title=Genetic variation in the transforming growth factor-{beta}1 gene is associated with susceptibility to IgA nephropathy. |OA=1 }}
Source and license
Adapted from rs2241715 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.