rs8179181
A SNP in the TGFB1 gene on chromosome 19. Its most notable genotype is G;G: common in clinvar
- Gene
- TGFB1
- Location
- Chr 1941,332,301 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 11%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs8179181 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageG;G 86%
- European ancestry (Utah)G;G 50%
- Han Chinese (Beijing)G;G 99%
- Yoruba (Nigeria)G;G 99%
- African ancestry (Southwest US)G;G 97%
- Gujarati IndianG;G 85%
- Luhya (Kenya)G;G 98%
- Mexican ancestry (Los Angeles)G;G 83%
- Maasai (Kenya)G;G 97%
- TuscanG;G 65%
Related
Other TGFB1 SNPs
- rs1800469G;Glower TGF-β1 levels, higher risk for COPD?Minor
- rs1800470A;GNo summary available.Typical
- rs1800471C;Ccommon in clinvarTypical
- rs1800472G;Gcommon on affy axiom dataTypical
- rs1982073G;Grisk genotype for several disordersTypical
- rs2241715A;Acommon in clinvarTypical
- rs4803455C;Ccommon in clinvarTypical
- rs8110090A;Acommon in complete genomicsTypical
Source and license
Adapted from rs8179181 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.