rs2266780
A SNP in the FMO3 gene on chromosome 1. Its most notable genotype is A;A: common in clinvar
- Gene
- FMO3
- Location
- Chr 1171,114,102 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 13%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageA;A 80%
- European ancestry (Utah)A;A 58%
- Han Chinese (Beijing)A;A 70%
- Japanese (Tokyo)A;A 67%
- Yoruba (Nigeria)A;A 97%
- African ancestry (Southwest US)A;A 91%
- Chinese (Denver)A;A 64%
- Gujarati IndianA;A 95%
- Mexican ancestry (Los Angeles)A;A 83%
- Maasai (Kenya)A;A 98%
- TuscanA;A 75%
Related
Other FMO3 SNPs
- rs61753344T;Ttrimethylaminuria & possible related issuesImportant
- rs72549320A;Atrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549321A;Atrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549322G;Gtrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549323C;Cpossible trimethylaminuria; see discussionWorth knowing
- rs72549326T;Ttrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549330T;Ttrimethylaminuria & related issues; see discussionWorth knowing
- rs72549331T;Ttrimethylaminuria & related issues; see discussionWorth knowing
Genosets
Genosets combine several genotypes. Twofold checks them in your report.
Source and license
Adapted from rs2266780 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.