rs72549322
A SNP in the FMO3 gene on chromosome 1. Its most notable genotype is G;G: trimethylaminuria & possible related issues; see discussion
- Gene
- FMO3
- Location
- Chr 1171,103,834 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AGoodcommon in clinvar
- A;GNot ratedlikely to be an unaffected carrier of a trimethylaminuria allele
- G;GMost notableBadtrimethylaminuria & possible related issues; see discussion
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other FMO3 SNPs
- rs61753344T;Ttrimethylaminuria & possible related issuesImportant
- rs72549320A;Atrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549321A;Atrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549323C;Cpossible trimethylaminuria; see discussionWorth knowing
- rs72549326T;Ttrimethylaminuria & possible related issues; see discussionWorth knowing
- rs72549330T;Ttrimethylaminuria & related issues; see discussionWorth knowing
- rs72549331T;Ttrimethylaminuria & related issues; see discussionWorth knowing
- rs72549332A;Atrimethylaminuria & possible related issues; see discussionWorth knowing
Notes
From SNPedia
Notes
rs72549322, also known as Asn61Ser, is a SNP in the FMO3 gene. In homozygous minor genotypes, it is likely to be lead to trimethylaminuria.
Source and license
Adapted from rs72549322 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.