rs2268494
A SNP in the OXTR gene on chromosome 3. Its most notable genotype is T;T.
- Gene
- OXTR
- Location
- Chr 38,760,360 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 6%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageT;T 87%
- European ancestry (Utah)T;T 89%
- Han Chinese (Beijing)T;T 80%
- Japanese (Tokyo)T;T 88%
- Yoruba (Nigeria)T;T 97%
- Chinese (Denver)T;T 85%
- Gujarati IndianT;T 76%
- Luhya (Kenya)T;T 90%
- Mexican ancestry (Los Angeles)T;T 90%
- Maasai (Kenya)T;T 90%
- TuscanT;T 83%
Related
Other OXTR SNPs
- rs53576A;ALack of empathy?Worth knowing
- rs1042778T;TSlightly lower oxytocin & empathy? Possibly higher 'callous-unemotional' trait frequency in children.Minor
- rs13316193C;Cslight evidence indicating increased OXTR expression, higher levels of empathy.Typical
- rs237885G;Tcommon in complete genomicsTypical
Source and license
Adapted from rs2268494 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.