rs2280714(T;T)

1.4x increased risk of SLE

Magnitude
1.5Minor
Repute
Bad
Frequency
36%Average of 11 populations
On SNPedia
rs2280714(A;A)Minus strand
Gene
TNPO3

Frequency

Share of people with T;T in each HapMap population.

  • Tuscan51%
  • Gujarati Indian46%
  • Chinese (Denver)38%
  • Yoruba (Nigeria)36%
  • European ancestry (Utah)35%
  • African ancestry (Southwest US)35%
  • Luhya (Kenya)35%
  • Mexican ancestry (Los Angeles)33%
  • Maasai (Kenya)33%
  • Japanese (Tokyo)29%
  • Han Chinese (Beijing)26%

Other genotypes of rs2280714

  1. C;TBad1.4x increased risk of SLEMinor · 1.548% of people
  2. C;CGoodNormal risk of SLEMinor · 1.016% of people

All about rs2280714

Source and license

Adapted from rs2280714(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.