IRF5
17 SNPs in the IRF5 gene, 3 with a genotype of magnitude 2 or higher.
- Type
- Gene
- SNPs
- 17
- Notable
- 3Magnitude 2 or higher
- Well documented
- 8
- Genosets
- 0
IRF5 SNPs
Every genotype, as shown in 23andMe and AncestryDNA files.
- rs10488631Important
- C;C2x increased risk of developing SLE; 3.2x increased risk of developing primary biliary cirrhosis; and 3.4x increased risk of developing Sjögren's syndromeBad
- C;T2x increased risk of developing SLE; 1.6x increased risk of developing primary biliary cirrhosis; and 1.7x increased risk of developing Sjögren's syndromeBad
- T;TNormal risk of developing SLE, primary biliary cirrhosis, and Sjögren's syndromeGood
- rs2004640Worth knowing
- rs10181656Worth knowing
- rs729302Minor
- rs2280714Minor
- rs6953165Typical
- rs7582694Typical
- rs41298401Typical
No matches.
Related
Conditions and medicines
Other SNPs
No notable genotype or detailed notes
Source and license
Adapted from IRF5 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.