rs2287074
A SNP in the MMP2 gene on chromosome 16. Its most notable genotype is G;G: common in clinvar
- Gene
- MMP2
- Location
- Chr 1655,493,201 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 35%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageG;G 45%
- European ancestry (Utah)G;G 23%
- Han Chinese (Beijing)G;G 51%
- Japanese (Tokyo)G;G 43%
- Yoruba (Nigeria)G;G 63%
Related
Notes
From SNPedia
Notes
association of the MMP-2 gene with the development of lacunar stroke. rs1030868, rs2241145, rs2287074, rs2287076, rs7201 showed a significant association with small vessel infarcts (p < 0.05) and rs7201:g.C was identified as an independent risk factor by multivariable logistic regression analysis
Source and license
Adapted from rs2287074 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.