rs7201

A SNP in the MMP2 gene on chromosome 16. Its most notable genotype is A;A: common in clinvar

Gene
MMP2
Location
Chr 1655,505,702 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
34%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in clinvarTypical · 0.051% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 51%
  • European ancestry (Utah)A;A 26%
  • Han Chinese (Beijing)A;A 55%
  • Japanese (Tokyo)A;A 52%
  • Yoruba (Nigeria)A;A 71%
  • African ancestry (Southwest US)A;A 58%
  • Chinese (Denver)A;A 57%
  • Gujarati IndianA;A 41%
  • Luhya (Kenya)A;A 77%
  • Mexican ancestry (Los Angeles)A;A 29%
  • Maasai (Kenya)A;A 71%
  • TuscanA;A 26%

Notes

From SNPedia

Notes

association of the MMP-2 gene with the development of lacunar stroke. rs1030868, rs2241145, rs2287074, rs2287076, rs7201 showed a significant association with small vessel infarcts (p < 0.05) and rs7201:g.C was identified as an independent risk factor by multivariable logistic regression analysis

Source and license

Adapted from rs7201 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.