rs2395185(G;G)

1.33x increased risk of Ulcerative Colitis, but much lower Type 1 Diabetes risk.

Magnitude
2.0Worth knowing
Repute
Good
Frequency
50%Average of 11 populations
On SNPedia
rs2395185(G;G)
Gene
None listed

Frequency

Share of people with G;G in each HapMap population.

  • Luhya (Kenya)76%
  • Yoruba (Nigeria)66%
  • African ancestry (Southwest US)65%
  • Tuscan57%
  • Maasai (Kenya)53%
  • Gujarati Indian48%
  • Han Chinese (Beijing)39%
  • Mexican ancestry (Los Angeles)39%
  • Chinese (Denver)38%
  • Japanese (Tokyo)36%
  • European ancestry (Utah)34%

Other genotypes of rs2395185

  1. G;TBad2.72x higher risk of Type 1 Diabetes, but 0.88x lower risk of Ulcerative Colitis.Worth knowing · 2.040% of people
  2. T;TMost notableBad9.49x risk of Type 1 Diabetes, but 0.58x lower risk of Ulcerative Colitis.Important · 3.010% of people

All about rs2395185

Notes

From SNPedia

This raises the risk of Ulcerative Colitis (according to 23andMe), but also greatly lowers the risk of Type 1 Diabetes. It may also affect other autoimmune diseases.

References

Source and license

Adapted from rs2395185(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.