rs2395185(G;T)

2.72x higher risk of Type 1 Diabetes, but 0.88x lower risk of Ulcerative Colitis.

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
40%Average of 11 populations
On SNPedia
rs2395185(G;T)
Gene
None listed

Frequency

Share of people with G;T in each HapMap population.

  • Japanese (Tokyo)52%
  • Mexican ancestry (Los Angeles)52%
  • Han Chinese (Beijing)48%
  • European ancestry (Utah)46%
  • Chinese (Denver)43%
  • Gujarati Indian42%
  • Tuscan38%
  • Maasai (Kenya)35%
  • Yoruba (Nigeria)31%
  • African ancestry (Southwest US)30%
  • Luhya (Kenya)21%

Other genotypes of rs2395185

  1. G;GGood1.33x increased risk of Ulcerative Colitis, but much lower Type 1 Diabetes risk.Worth knowing · 2.050% of people
  2. T;TMost notableBad9.49x risk of Type 1 Diabetes, but 0.58x lower risk of Ulcerative Colitis.Important · 3.010% of people

All about rs2395185

Notes

From SNPedia

This lowers the risk of Ulcerative Colitis (according to 23andMe), and increases the risk of Type 1 Diabetes.PMID 19837788 It may also affect other autoimmune diseases.

References

Source and license

Adapted from rs2395185(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.