rs267606655

A SNP in the ANGPTL3 gene on chromosome 1. Its most notable genotype is CC;GA: Lowered risk (0.6x) of coronary artery disease

Gene
ANGPTL3
Location
Chr 162,597,616 (GRCh38)
Highest magnitude
5.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. CC;CCGoodcommon in clinvarTypical · 0.0
  2. CC;GAMost notableGoodLowered risk (0.6x) of coronary artery diseaseVery important · 5.0

On SNPedia: (CC;CC), (CC;GA). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other ANGPTL3 SNPs

All ANGPTL3 SNPs

Notes

From SNPedia

Notes

rs267606655, also known as c.50_51delCCinsGA and p.Ser17Ter, represents a rare loss of function variant in the ANGPTL3 gene on chromosome 1. As a loss of function variant, the minor allele leads to lower amounts of ANGPTL3 protein, lowered triglycerides and LDL cholesterol, and according to several studies, a lowered risk (by about 40%) of developing coronary artery disease. These studies are discussed on the ANGPTL3 page.

CC;GA

see ANGPTL3 page and rs267606655

Source and license

Adapted from rs267606655 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.