rs398122987

A SNP in the ANGPTL3 gene on chromosome 1. Its most notable genotype is -;AACT: Lowered risk (0.6x) of coronary artery disease

Gene
ANGPTL3
Location
Chr 162,598,005 (GRCh38)
Highest magnitude
5.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;AACTMost notableGoodLowered risk (0.6x) of coronary artery diseaseVery important · 5.0
  2. AACT;AACTGoodcommon in clinvarTypical · 0.0

On SNPedia: (-;AACT), (AACT;AACT). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other ANGPTL3 SNPs

All ANGPTL3 SNPs

Notes

From SNPedia

Notes

ANGPTL3, c.439_442delAACT (p.Asn147Terfs)

-;AACT

see ANGPTL3 page

Source and license

Adapted from rs398122987 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.