rs267606993
A SNP in the PYGM gene on chromosome 11. Its most notable genotype is G;G: McArdle disease (also known as glycogen storage disease type V)
- Gene
- PYGM
- Location
- Chr 1164,759,898 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in clinvar
- G;TBadCarrier of a McArdle disease mutation
- G;GMost notableBadMcArdle disease (also known as glycogen storage disease type V)
SNPedia records rs267606993 on the minus strand: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other PYGM SNPs
- rs116987552A;AMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103251T;TMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103252G;GMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103253T;TMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103254G;GMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103255A;AMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103256C;CMcArdle disease (also known as glycogen storage disease type V)Very important
- rs119103257A;AMcArdle disease (also known as glycogen storage disease type V)Very important
Notes
From SNPedia
Notes
PYGM gene, c.1A>C, p.Met1Leu or M1L 23andMe name for A>G variant (not the A>C variant): i5005806
G;T
Unaffected in absence of a second mutation in the PYGM gene
Source and license
Adapted from rs267606993 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.