rs2710117
A SNP in the CNTNAP2 gene on chromosome 7. Its most notable genotype is A;A: higher risk of speech development delay and/or impairment
- Gene
- CNTNAP2
- Location
- Chr 7147,904,680 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 37%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableBadhigher risk of speech development delay and/or impairment
- A;TNot ratedNo summary available.
- T;TNot ratedNo summary available.
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageA;A 41% A;T 47% T;T 12%
- European ancestry (Utah)A;A 40% A;T 42% T;T 19%
- Han Chinese (Beijing)A;A 40% A;T 42% T;T 18%
- Japanese (Tokyo)A;A 50% A;T 48% T;T 2%
- Yoruba (Nigeria)A;A 33% A;T 57% T;T 10%
Related
Conditions, medicines and genes
Other CNTNAP2 SNPs
- rs2710102A;ADelayed childhood speech.Worth knowing
- rs7794745A;Tslightly increased risk for autismWorth knowing
- rs17236239G;Ghigher risk for speech development delay and/or impairmentWorth knowing
- rs851715T;Trisk of nonsense-word repetition problems if speech-impairedMinor
- rs759178C;Chigher risk of speech development delay and/or impairmentTypical
- rs802568T;Tcommon in complete genomicsTypical
- rs1358075T;Tcommon genotypeTypical
- rs1718101C;CNo summary available.Typical
Notes
From SNPedia
Notes
Speech development rs4431523, rs17236239 and significant associations (with P values from 0.01 to 5.0x10–5) between nonsense-word repetition and nine intronic SNPs (rs851715, rs10246256, rs2710102, rs759178, rs1922892, rs2538991, rs17236239, rs2538976, and rs2710117)
Source and license
Adapted from rs2710117 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.