rs28933380
A SNP in the APC gene on chromosome 5. Its most notable genotype is A;A: risk of colon cancer
- Gene
- APC
- Location
- Chr 5112,839,514 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableBadrisk of colon cancer
- A;TBadrisk of colon cancer
- T;TGoodNo summary available.
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other APC SNPs
- rs2229992G;TFamilial Adenomatous PolyposisVery important
- rs62619935C;TFamilial Adenomatous PolyposisVery important
- rs121913331C;TFamilial Adenomatous PolyposisVery important
- rs121913333C;TFamilial Adenomatous PolyposisVery important
- rs137854568C;TFamilial Adenomatous PolyposisVery important
- rs137854569C;GFamilial Adenomatous PolyposisVery important
- rs137854572C;TFamilial Adenomatous PolyposisVery important
- rs137854575A;CFamilial Adenomatous PolyposisVery important
Notes
From SNPedia
Notes
colon cancer
Source and license
Adapted from rs28933380 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.