rs28938172
A SNP in the PARK7 gene on chromosome 1. Its most notable genotype is C;C: Parkinson's disease, type 7, early-onset
- Gene
- PARK7
- Location
- Chr 17,984,981 (GRCh38)
- Highest magnitude
- 8.7Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CMost notableBadParkinson's disease, type 7, early-onset
- C;TBadCarrier of an early-onset Parkinson's mutation
- T;TGoodcommon in complete genomics
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other PARK7 SNPs
- rs74315351A;AParkinson's disease, type 7, early-onsetVery important
- rs74315352C;CParkinson's disease, type 7, early-onsetVery important
- rs74315353C;CParkinson's disease, type 7, early-onsetVery important
- rs74315354A;AParkinson's disease, type 7, early-onset (likely)Very important
- rs137853051T;TParkinson's disease, type 7, early-onsetVery important
Notes
From SNPedia
Notes
c.497T>C (p.Leu166Pro or L166P) Considered "definitely pathogenic" in the Movement Disorder Society Genetic mutation database (MDSGene) for autosomal recessive, early-onset Parkinson disease (type 7) See also OMIM 602533.0002 23andMe calls this i5047042
C;C
see Parkinson's disease and PARK7
C;T
see Parkinson's disease and PARK7
Source and license
Adapted from rs28938172 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.