rs3732183
A SNP in the MSH2 gene on chromosome 2. Its most notable genotype is G;G: common in clinvar
- Gene
- MSH2
- Location
- Chr 247,466,820 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 47%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 26%
- European ancestry (Utah)G;G 51%
- Han Chinese (Beijing)G;G 14%
- Japanese (Tokyo)G;G 13%
- Yoruba (Nigeria)G;G 7%
- African ancestry (Southwest US)G;G 13%
- Chinese (Denver)G;G 12%
- Gujarati IndianG;G 48%
- Luhya (Kenya)G;G 8%
- Mexican ancestry (Los Angeles)G;G 55%
- Maasai (Kenya)G;G 10%
- TuscanG;G 58%
Related
Other MSH2 SNPs
- rs63750245T;TLynch syndrome; hereditary nonpolyposis colorectal cancer-1Very important
- rs63750875C;CLynch syndrome; hereditary nonpolyposis colorectal cancer (HNPCC1)Very important
- rs63751449-;-Lynch syndrome; hereditary nonpolyposis colorectal cancer-1Very important
- rs12476364A;GLynch syndrome, pathogenic mutationVery important
- rs28929483C;TLynch syndrome, pathogenic mutationVery important
- rs28929484C;TLynch syndrome, pathogenic mutationVery important
- rs34986638G;TLynch syndrome, pathogenic mutationVery important
- rs63749802G;TLynch syndrome, pathogenic mutationVery important
Source and license
Adapted from rs3732183 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.