rs377767378
A SNP in the SMAD4 gene on chromosome 18. Its most notable genotype is -;G.
- Gene
- SMAD4
- Location
- Chr 1851,078,402 (GRCh38)
- Highest magnitude
- 4.0Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;GMost notableBadNo summary available.
- G;GGoodcommon in clinvar
On SNPedia: (-;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other SMAD4 SNPs
- rs80338963C;GJuvenile polyposis syndromeVery important
- rs80338965-;CAGAJuvenile polyposis syndromeVery important
- rs121912581A;GNo summary available.Very important
- rs281875320A;GJuvenile polyposis syndromeVery important
- rs281875321C;TJuvenile polyposis syndromeVery important
- rs281875322A;GJuvenile polyposis syndromeVery important
- rs281875324A;GJuvenile polyposis syndromeVery important
- rs377767328-;TCJuvenile polyposis syndromeVery important
Notes
From SNPedia
Notes
-;G
Hereditary hemorrhagic telangiectasia?
Source and license
Adapted from rs377767378 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.