rs3785143

A SNP in the SLC6A2 gene on chromosome 16. Its most notable genotype is C;T: may be associated with ADHD

Gene
SLC6A2
Location
Chr 1655,661,194 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA
Minor allele frequency
10%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodnormal risk of ADHDTypical · 0.082% of people
  2. C;TMost notableNot ratedmay be associated with ADHDMinor · 1.017% of people
  3. T;TNot ratedmay be associated with ADHDMinor · 1.01% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 82% C;T 17% T;T 1%
  • European ancestry (Utah)C;C 82% C;T 18% T;T 0%
  • Han Chinese (Beijing)C;C 74% C;T 19% T;T 7%
  • Japanese (Tokyo)C;C 66% C;T 31% T;T 3%
  • Yoruba (Nigeria)C;C 99% C;T 1% T;T 0%
  • African ancestry (Southwest US)C;C 91% C;T 9% T;T 0%
  • Chinese (Denver)C;C 71% C;T 26% T;T 4%
  • Gujarati IndianC;C 71% C;T 28% T;T 1%
  • Luhya (Kenya)C;C 96% C;T 4% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 71% C;T 29% T;T 0%
  • Maasai (Kenya)C;C 92% C;T 8% T;T 0%
  • TuscanC;C 85% C;T 14% T;T 1%

Conditions, medicines and genes

Other SLC6A2 SNPs

All SLC6A2 SNPs

Notes

From SNPedia

Notes

T allele may be associated with Attention deficit hyperactivity disorder.

Source and license

Adapted from rs3785143 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.