rs998424
A SNP in the SLC6A2 gene on chromosome 16. Its most notable genotype is G;G: common in clinvar
- Gene
- SLC6A2
- Location
- Chr 1655,698,034 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 27%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs998424 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SLC6A2 SNPs
- rs3785143C;Tmay be associated with ADHDMinor
- rs5558A;ANo summary available.Typical
- rs5568A;Acommon in clinvarTypical
- rs5569G;Gcommon in clinvarTypical
- rs187715T;TNo summary available.Typical
- rs734980A;Acommon in complete genomicsTypical
- rs2242446C;Ccommon in clinvarTypical
- rs3785152C;Ccommon in complete genomicsTypical
Notes
From SNPedia
Notes
Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults. Further evidence of association between two NET single-nucleotide polymorphisms with ADHD. Lack of association between response of OROS-methylphenidate and norepinephrine transporter (SLC6A2) polymorphism in Korean ADHD. Genetic influences on attention deficit hyperactivity disorder symptoms from age 2 to 3: a quantitative and molecular genetic investigation. Support for association between ADHD and two candidate genes: NET1 and DRD1.
Source and license
Adapted from rs998424 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.