rs387906299
A SNP in the COQ8A gene on chromosome 1. Its most notable genotype is -;-: Coenzyme Q10 Deficiency; severity varies
- Gene
- COQ8A
- Location
- Chr 1226,986,543 (GRCh38)
- Highest magnitude
- 5.6Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Most notableBadCoenzyme Q10 Deficiency; severity varies
- -;ACCBadCarrier of a coenzyme Q10 deficiency mutation
- ACC;ACCGoodcommon in clinvar
- CAC;CACGoodcommon in clinvar
On SNPedia: (-;-), (-;ACC), (ACC;ACC), (CAC;CAC). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other COQ8A SNPs
- rs145034527T;TPossible Coenzyme Q10 Deficiency; severity variesVery important
- rs387906298G;GCoenzyme Q10 Deficiency; severity variesVery important
- rs578189699T;TCoenzyme Q10 Deficiency; severity variesVery important
- rs606231138C;CCoenzyme Q10 Deficiency; severity variesVery important
- rs606231139TTG;TTGCoenzyme Q10 Deficiency; severity variesVery important
- rs771578775T;TCoenzyme Q10 Deficiency; severity variesVery important
- rs797045217-;-Coenzyme Q10 Deficiency; severity variesVery important
- rs886043382A;ACoenzyme Q10 Deficiency; severity variesVery important
Notes
From SNPedia
Notes
-;-
see coenzyme Q10 deficiency
-;ACC
Unaffected in absence of a second mutation; see coenzyme Q10 deficiency
Source and license
Adapted from rs387906299 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.