rs387906546
A SNP in the FH gene on chromosome 1. Its most notable genotype is G;T: Associated with leiomyomatosis and possibly renal cell cancer
- Gene
- FH
- Location
- Chr 1241,517,258 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- Not on consumer chips
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in clinvar
- G;TMost notableBadAssociated with leiomyomatosis and possibly renal cell cancer
SNPedia records rs387906546 on the minus strand: (A;A), (A;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other FH SNPs
- rs367543046AAA;AAAFumarase deficiency (predicted)Very important
- rs75086406C;GAssociated with leiomyomatosis and possibly renal cell cancerVery important
- rs121913120A;GHereditary leiomyomatosis and renal cell cancerVery important
- rs121913121G;TAssociated with leiomyomatosis and possibly renal cell cancerVery important
- rs121913122A;GHereditary leiomyomatosis and renal cell cancerVery important
- rs121913123C;TAssociated with leiomyomatosis and possibly renal cell cancerVery important
- rs398123160A;GHereditary leiomyomatosis and renal cell cancerVery important
- rs398123163-;THereditary leiomyomatosis and renal cell cancerVery important
Notes
From SNPedia
Notes
G;T
see Hereditary leiomyomatosis and renal cell cancer
Source and license
Adapted from rs387906546 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.