rs397518439

A SNP in the PACRG gene on chromosome 6. Its most notable genotype is A;A: Early-onset (juvenile) Parkinson's disease likely

Gene
PACRG
Location
Chr 6162,727,661 (GRCh38)
Highest magnitude
9.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.0
  2. A;CBadCarrier of an early-onset Parkinson's mutationImportant · 3.0
  3. A;AMost notableBadEarly-onset (juvenile) Parkinson's disease likelyVery important · 9.0

SNPedia records rs397518439 on the minus strand: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

c.7+1G>T

A;C

see Parkinson's disease and PARK2

A;A

See Parkinson's disease and PARK2

Source and license

Adapted from rs397518439 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.