rs398123111
A SNP in the ABCD1 gene on chromosome X. Its most notable genotype is T;T: Possible Ancestry miscall; otherwise, X-linked adrenoleukodystrophy; symptoms and age of onset highly variable
- Gene
- ABCD1
- Location
- Chr X153,725,672 (GRCh38)
- Highest magnitude
- 7.7Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- C;TBadPossible Ancestry miscall; otherwise, Carrier of of X-linked adrenoleukodystrophy mutation; AMN symptoms possible
- T;TMost notableBadPossible Ancestry miscall; otherwise, X-linked adrenoleukodystrophy; symptoms and age of onset highly variable
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ABCD1 SNPs
- rs74315277G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs74315278-;-X-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs74315280A;AX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624213A;AX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624214G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624215G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624216G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624217G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
Notes
From SNPedia
Notes
aka c.406C>T (p.Gln136Ter)
Source and license
Adapted from rs398123111 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.