rs398123112
A SNP in the ABCD1 gene on chromosome X. Its most notable genotype is -;-: X-linked adrenoleukodystrophy; symptoms and age of onset highly variable
- Gene
- ABCD1
- Location
- Chr X153,725,764 (GRCh38)
- Highest magnitude
- 7.7Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Most notableBadX-linked adrenoleukodystrophy; symptoms and age of onset highly variable
- -;GGTGGCCCACGCCTACCGCCTCTBadCarrier of of X-linked adrenoleukodystrophy mutation; AMN symptoms possible
- GGTGGCCCACGCCTACCGCCTCT;GGTGGCCCACGCCTACCGCCTCTGoodcommon in clinvar
- TCTGGTGGCCCACGCCTACCGCC;TCTGGTGGCCCACGCCTACCGCCGoodcommon in clinvar
On SNPedia: (-;-), (-;GGTGGCCCACGCCTACCGCCTCT), (GGTGGCCCACGCCTACCGCCTCT;GGTGGCCCACGCCTACCGCCTCT), (TCTGGTGGCCCACGCCTACCGCC;TCTGGTGGCCCACGCCTACCGCC). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ABCD1 SNPs
- rs74315277G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs74315278-;-X-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs74315280A;AX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624213A;AX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624214G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624215G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624216G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
- rs128624217G;GX-linked adrenoleukodystrophy; symptoms and age of onset highly variableVery important
Notes
From SNPedia
Notes
c.498_520del23 (p.Val167Leufs)
Source and license
Adapted from rs398123112 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.