rs4146894(C;T)

2.6x risk for AMD

Magnitude
0.0Typical
Repute
Not rated
Frequency
48%Average of 11 populations
On SNPedia
rs4146894(A;G)Minus strand
Gene
PLEKHA1

Frequency

Share of people with C;T in each HapMap population.

  • African ancestry (Southwest US)56%
  • Mexican ancestry (Los Angeles)54%
  • Gujarati Indian52%
  • Chinese (Denver)51%
  • Japanese (Tokyo)50%
  • Maasai (Kenya)47%
  • European ancestry (Utah)47%
  • Tuscan47%
  • Yoruba (Nigeria)45%
  • Han Chinese (Beijing)44%
  • Luhya (Kenya)41%

Other genotypes of rs4146894

  1. T;TMost notableNot rated9.1x risk for AMD, but replication is lackingWorth knowing · 2.123% of people
  2. C;CNot ratedaverageTypical · 0.028% of people

All about rs4146894

Source and license

Adapted from rs4146894(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.