rs4363657(C;C)

17x increased myopathy risk for statin users

Magnitude
4.0Very important
Repute
Bad
Frequency
8%Average of 11 populations
On SNPedia
rs4363657(C;C)
Gene
SLCO1B1

Frequency

Share of people with C;C in each HapMap population.

  • Chinese (Denver)28%
  • Han Chinese (Beijing)23%
  • Japanese (Tokyo)18%
  • African ancestry (Southwest US)5%
  • Maasai (Kenya)5%
  • Tuscan4%
  • Luhya (Kenya)2%
  • Mexican ancestry (Los Angeles)2%
  • Yoruba (Nigeria)1%
  • European ancestry (Utah)<1%
  • Gujarati Indian0%

Other genotypes of rs4363657

  1. C;TBad4.5x increased myopathy risk for statin usersWorth knowing · 2.131% of people
  2. T;TGoodnormalTypical · 0.061% of people

All about rs4363657

Source and license

Adapted from rs4363657(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.