rs4363657(C;T)

4.5x increased myopathy risk for statin users

Magnitude
2.1Worth knowing
Repute
Bad
Frequency
31%Average of 11 populations
On SNPedia
rs4363657(C;T)
Gene
SLCO1B1

Frequency

Share of people with C;T in each HapMap population.

  • Han Chinese (Beijing)44%
  • Japanese (Tokyo)43%
  • Chinese (Denver)41%
  • Tuscan37%
  • African ancestry (Southwest US)32%
  • European ancestry (Utah)31%
  • Maasai (Kenya)28%
  • Luhya (Kenya)27%
  • Yoruba (Nigeria)25%
  • Mexican ancestry (Los Angeles)18%
  • Gujarati Indian13%

Other genotypes of rs4363657

  1. C;CMost notableBad17x increased myopathy risk for statin usersVery important · 4.08% of people
  2. T;TGoodnormalTypical · 0.061% of people

All about rs4363657

Source and license

Adapted from rs4363657(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.