rs4489954(G;T)

0.69x risk risk of developing restless legs syndrome

Magnitude
1.5Minor
Repute
Good
Frequency
45%Average of 11 populations
On SNPedia
rs4489954(G;T)
Gene
MAP2K5

Frequency

Share of people with G;T in each HapMap population.

  • Yoruba (Nigeria)54%
  • African ancestry (Southwest US)51%
  • Mexican ancestry (Los Angeles)48%
  • Maasai (Kenya)46%
  • Han Chinese (Beijing)46%
  • European ancestry (Utah)46%
  • Gujarati Indian45%
  • Japanese (Tokyo)42%
  • Chinese (Denver)40%
  • Luhya (Kenya)39%
  • Tuscan39%

Other genotypes of rs4489954

  1. G;GBadNormal risk of developing restless legs syndromeMinor · 1.030% of people
  2. T;TMost notableGood>0.69x risk of developing restless legs syndromeMinor · 1.825% of people

All about rs4489954

Source and license

Adapted from rs4489954(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.