rs45514002

A SNP in the LDB3 gene on chromosome 10. Its most notable genotype is A;G: left ventricular noncompaction (reported)

Gene
LDB3
Location
Chr 1086,726,175 (GRCh38)
Highest magnitude
4.0Very important
Tested on
23andMe, AncestryDNA
Minor allele frequency
<1%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableBadleft ventricular noncompaction (reported)Very important · 4.0
  2. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other LDB3 SNPs

All LDB3 SNPs

Notes

From SNPedia

Notes

rs45514002, also known as c.2017G>A, p.Asp673Asn and D673N as well as Asp626Asn, is a rare mutation in the LDB3 gene on chromosome 10. Inherited as an autosomal dominant, it reportedly leads to a form of left ventricular noncompaction. See OMIM 605906.0009

A;G

see discussion at rs45514002

Source and license

Adapted from rs45514002 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.