rs4752566
A SNP in the FGFR2 gene on chromosome 10. Its most notable genotype is G;T: associated with thicker hair in Asians
- Gene
- FGFR2
- Location
- Chr 10121,508,117 (GRCh38)
- Highest magnitude
- 1.0Minor
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 49%
Genotypes
As shown in 23andMe and AncestryDNA files.
- G;TMost notableGoodassociated with thicker hair in Asians
- T;TGoodassociated with thicker hair in Asians
On SNPedia: (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;T 31% T;T 33%
- European ancestry (Utah)G;T 51% T;T 19%
- Han Chinese (Beijing)G;T 19% T;T 78%
- Japanese (Tokyo)G;T 13% T;T 87%
- Yoruba (Nigeria)G;T 20% T;T <1%
- African ancestry (Southwest US)G;T 16% T;T 2%
- Chinese (Denver)G;T 16% T;T 84%
- Gujarati IndianG;T 41% T;T 46%
- Luhya (Kenya)G;T 24% T;T 0%
- Mexican ancestry (Los Angeles)G;T 54% T;T 18%
- Maasai (Kenya)G;T 39% T;T 5%
- TuscanG;T 53% T;T 21%
Related
Other FGFR2 SNPs
- rs2981582A;A1.7x higher risk of ER+ breast cancerImportant
- rs3750817T;T0.64x reduced risk for breast cancer, and higher likelihood of favorable postmenopausal hormone therapyWorth knowing
- rs1219648G;G1.64x risk for breast cancerWorth knowing
- rs2420946T;T1.64x risk for breast cancerWorth knowing
- rs755793A;Acommon in complete genomicsTypical
- rs1047100T;Tcommon in clinvarTypical
- rs2303568A;Acommon in complete genomicsTypical
- rs2981578T;TnormalTypical
Notes
From SNPedia
Notes
Significantly associated statistically with thicker hair in Asians; effect in non-Asians not known at time of this 2009 publication.
Source and license
Adapted from rs4752566 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.