rs4988300

A SNP in the LRP5 gene on chromosome 11. Its most notable genotype is G;T.

Gene
LRP5
Location
Chr 1168,321,363 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
43%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;TMost notableNot ratedNo summary available.Typical · 0.041% of people

On SNPedia: (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;T 41%
  • European ancestry (Utah)G;T 45%
  • Han Chinese (Beijing)G;T 31%
  • Japanese (Tokyo)G;T 34%
  • Yoruba (Nigeria)G;T 50%
  • African ancestry (Southwest US)G;T 44%
  • Chinese (Denver)G;T 34%
  • Gujarati IndianG;T 22%
  • Luhya (Kenya)G;T 49%
  • Mexican ancestry (Los Angeles)G;T 43%
  • Maasai (Kenya)G;T 50%
  • TuscanG;T 47%

Conditions, medicines and genes

Notes

From SNPedia

Notes

linked to obesity

Source and license

Adapted from rs4988300 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.