rs500760

A SNP in the PGR gene on chromosome 11. Its most notable genotype is C;C.

Gene
PGR
Location
Chr 11101,039,260 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
29%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TNot ratedNo summary available.Typical · 0.051% of people
  2. C;TNot ratedNo summary available.Typical · 0.040% of people
  3. C;CMost notableNot ratedNo summary available.Typical · 0.09% of people

SNPedia records rs500760 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 51% C;T 40% C;C 9%
  • European ancestry (Utah)T;T 57% C;T 35% C;C 8%
  • Han Chinese (Beijing)T;T 64% C;T 32% C;C 4%
  • Japanese (Tokyo)T;T 62% C;T 28% C;C 10%
  • Yoruba (Nigeria)T;T 37% C;T 52% C;C 11%
  • African ancestry (Southwest US)T;T 44% C;T 46% C;C 11%
  • Chinese (Denver)T;T 55% C;T 40% C;C 5%
  • Gujarati IndianT;T 77% C;T 22% C;C 1%
  • Luhya (Kenya)T;T 29% C;T 51% C;C 20%
  • Mexican ancestry (Los Angeles)T;T 45% C;T 41% C;C 14%
  • Maasai (Kenya)T;T 34% C;T 52% C;C 14%
  • TuscanT;T 58% C;T 36% C;C 6%

Conditions, medicines and genes

Other PGR SNPs

All PGR SNPs

Notes

From SNPedia

Notes

This SNP in the progesterone receptor PGR gene is not likely to increase the risk of breast cancer.

Source and license

Adapted from rs500760 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.