rs503362

A SNP in the PGR gene on chromosome 11. Its most notable genotype is C;G.

Gene
PGR
Location
Chr 11101,091,096 (GRCh38)
Highest magnitude
0.1Typical
Tested on
23andMe
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;GMost notableNot ratedNo summary available.Typical · 0.130% of people
  2. G;GNot ratedNo summary available.Typical · 0.064% of people

On SNPedia: (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageC;G 30% G;G 64%
  • European ancestry (Utah)C;G 44% G;G 54%
  • Han Chinese (Beijing)C;G <1% G;G 99%
  • Japanese (Tokyo)C;G 3% G;G 97%
  • Yoruba (Nigeria)C;G 49% G;G 40%
  • Gujarati IndianC;G 30% G;G 58%
  • Luhya (Kenya)C;G 37% G;G 51%
  • Mexican ancestry (Los Angeles)C;G 27% G;G 71%
  • TuscanC;G 47% G;G 43%

Conditions, medicines and genes

Other PGR SNPs

All PGR SNPs

Notes

From SNPedia

Notes

news The effectiveness of 17 alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth is influenced by SNPs. Black women *rs471767 homozygous for the major allele treatment significantly reduced the rate of preterm birth. *rs578029 who had a least one copy of the major allele, treatment significantly reduced in preterm birth non-black women *a least one copy of the minor allele of rs503362 had a significant reduction with treatment *with at least one copy of the minor allele of rs666553 had a significant reduction in very preterm birth

Source and license

Adapted from rs503362 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.