rs5029937

A SNP in the TNFAIP3 gene on chromosome 6. Its most notable genotype is G;G.

Gene
TNFAIP3
Location
Chr 6137,874,014 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodNo summary available.Typical · 0.065% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageG;G 65%
  • European ancestry (Utah)G;G 92%
  • Han Chinese (Beijing)G;G 82%
  • Japanese (Tokyo)G;G 64%
  • Yoruba (Nigeria)G;G 22%

Conditions, medicines and genes

Other TNFAIP3 SNPs

All TNFAIP3 SNPs

Notes

From SNPedia

Notes

rheumatoid arthritis *rs6920220 [P= 2.6 x 10(-6), OR 1.22 (1.13-1.33)]. *rs5029937 *rs13207033 protective [P= 0.0001, OR 0.86 (0.8-0.93)] perfectly correlated with rs10499194 The combination of the carriage of both risk alleles of rs6920220 and rs5029937 together with the absence of the protective allele of rs13207033 was strongly associated with RA when compared to carriage of none [OR of 1.86 (95% CI) (1.51-2.29)]. This equates to an effect size of 1.50 (95% CI 1.21-1.85)

Source and license

Adapted from rs5029937 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.