rs5370(G;T)

Possibly lower HDL cholesterol in women

Magnitude
1.2Minor
Repute
Bad
Frequency
34%Average of 11 populations
On SNPedia
rs5370(G;T)
Gene
EDN1

Frequency

Share of people with G;T in each HapMap population.

  • Gujarati Indian46%
  • Japanese (Tokyo)43%
  • Han Chinese (Beijing)40%
  • Chinese (Denver)38%
  • Tuscan36%
  • Maasai (Kenya)31%
  • Yoruba (Nigeria)31%
  • European ancestry (Utah)30%
  • African ancestry (Southwest US)28%
  • Mexican ancestry (Los Angeles)28%
  • Luhya (Kenya)23%

Other genotypes of rs5370

  1. G;GNot ratedcommonTypical · 0.060% of people
  2. T;TBadpossibly lower HDL cholesterol in womenMinor · 1.26% of people

All about rs5370

Notes

From SNPedia

One report indicates that women (but not men) with this genotype may have slightly lower levels of HDL cholesterol, but other reports have not observed this.

Source and license

Adapted from rs5370(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.