rs5443(T;T)

Viagra is more likely to have an effect. increased metabolic disease risk.

Magnitude
2.4Worth knowing
Repute
Bad
Frequency
30%Average of 4 populations
On SNPedia
rs5443(T;T)
Gene
GNB3

Frequency

Share of people with T;T in each HapMap population.

  • Yoruba (Nigeria)84%
  • Japanese (Tokyo)18%
  • European ancestry (Utah)10%
  • Han Chinese (Beijing)9%

Other genotypes of rs5443

  1. C;CGoodnormal, but higher risk for several conditionsMinor · 1.529% of people
  2. C;TBadsome riskWorth knowing · 2.141% of people

All about rs5443

Notes

From SNPedia

linked to a number of metabolic conditions including obesity, coronary artery disease, insulin resistance and therefore diabetes, left ventricular hypertrophy, and hypertension. It has also been linked to how well a patient responds to Viagra (sildenafil).

Source and license

Adapted from rs5443(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.