rs587781266
A SNP in the SDHB gene on chromosome 1. Its most notable genotype is -;CTCT: Hereditary PGL/PCC Syndrome
- Gene
- SDHB
- Location
- Chr 117,022,654 (GRCh38)
- Highest magnitude
- 6.2Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;CTCTMost notableBadHereditary PGL/PCC Syndrome
- CTCT;CTCTGoodcommon in clinvar
On SNPedia: (-;CTCT), (CTCT;CTCT). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SDHB SNPs
- rs74315366A;GHereditary PGL/PCC SyndromeVery important
- rs74315367C;GHereditary PGL/PCC SyndromeVery important
- rs74315368C;THereditary PGL/PCC SyndromeVery important
- rs74315369A;GHereditary PGL/PCC SyndromeVery important
- rs74315370C;GHereditary PGL/PCC SyndromeVery important
- rs74315371C;THereditary PGL/PCC SyndromeVery important
- rs74315372G;THereditary PGL/PCC SyndromeVery important
- rs138996609A;GHereditary PGL/PCC SyndromeVery important
Source and license
Adapted from rs587781266 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.