rs6445
A SNP in the CYP21A2 gene on chromosome 6. Its most notable genotype is T;T: Congenital adrenal hyperplasia
- Gene
- CYP21A2
- Location
- Chr 632,041,006 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in complete genomics
- C;TBadCarrier of allele for congenital adrenal hyperplasia
- T;TMost notableBadCongenital adrenal hyperplasia
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other CYP21A2 SNPs
- rs6471T;TCongenital adrenal hyperplasiaVery important
- rs6475A;ACongenital adrenal hyperplasiaVery important
- rs6476A;ACongenital adrenal hyperplasiaVery important
- rs7755898T;TCongenital adrenal hyperplasiaVery important
- rs151344503A;ACongenital adrenal hyperplasiaVery important
- rs151344505A;ACongenital adrenal hyperplasiaVery important
- rs201552310A;ACongenital adrenal hyperplasiaVery important
- rs267606757C;CCongenital adrenal hyperplasiaVery important
Notes
From SNPedia
Notes
C;T
See discussion at Congenital adrenal hyperplasia
T;T
See discussion at Congenital adrenal hyperplasia
Source and license
Adapted from rs6445 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.