rs6495446(C;C)

Normal, but increased risk for chronic kidney disease

Magnitude
1.0Minor
Repute
Bad
Frequency
48%Average of 11 populations
On SNPedia
rs6495446(C;C)
Gene
MTHFS

Frequency

Share of people with C;C in each HapMap population.

  • Gujarati Indian72%
  • European ancestry (Utah)62%
  • Mexican ancestry (Los Angeles)61%
  • Japanese (Tokyo)58%
  • Chinese (Denver)57%
  • Han Chinese (Beijing)53%
  • Tuscan53%
  • Maasai (Kenya)33%
  • African ancestry (Southwest US)28%
  • Luhya (Kenya)28%
  • Yoruba (Nigeria)26%

Other genotypes of rs6495446

  1. C;TGood0.8x reduced risk for chronic kidney diseaseMinor · 1.440% of people
  2. T;TMost notableGood0.64x reduced risk for chronic kidney diseaseWorth knowing · 2.011% of people

All about rs6495446

Notes

From SNPedia

in a small unreplicated study

Source and license

Adapted from rs6495446(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.