rs6495446(C;T)

0.8x reduced risk for chronic kidney disease

Magnitude
1.4Minor
Repute
Good
Frequency
40%Average of 11 populations
On SNPedia
rs6495446(C;T)
Gene
MTHFS

Frequency

Share of people with C;T in each HapMap population.

  • African ancestry (Southwest US)56%
  • Yoruba (Nigeria)50%
  • Maasai (Kenya)45%
  • Luhya (Kenya)42%
  • Tuscan42%
  • Han Chinese (Beijing)40%
  • Chinese (Denver)40%
  • Japanese (Tokyo)39%
  • European ancestry (Utah)36%
  • Mexican ancestry (Los Angeles)32%
  • Gujarati Indian23%

Other genotypes of rs6495446

  1. C;CBadnormal, but increased risk for chronic kidney diseaseMinor · 1.048% of people
  2. T;TMost notableGood0.64x reduced risk for chronic kidney diseaseWorth knowing · 2.011% of people

All about rs6495446

Source and license

Adapted from rs6495446(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.