rs7019241

A SNP in the GOLM1 gene on chromosome 9. Its most notable genotype is C;C: average

Gene
GOLM1
Location
Chr 986,078,545 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
26%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedaverageTypical · 0.051% of people
  2. C;TNot ratedreduced risk for AD?Typical · 0.036% of people
  3. G;GNot ratedNo summary available.Typical · 0.00% of people
  4. T;TNot ratedreduced risk for AD?Typical · 0.013% of people

On SNPedia: (C;C), (C;T), (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 51% C;T 36% G;G 0% T;T 13%
  • European ancestry (Utah)C;C 87% C;T 12% G;G 0% T;T <1%
  • Han Chinese (Beijing)C;C 19% C;T 53% G;G 0% T;T 29%
  • Japanese (Tokyo)C;C 20% C;T 48% G;G 0% T;T 32%
  • Yoruba (Nigeria)C;C 36% C;T 52% G;G 0% T;T 12%
  • African ancestry (Southwest US)C;C 46% C;T 42% G;G 0% T;T 12%
  • Chinese (Denver)C;C 23% C;T 45% G;G 0% T;T 32%
  • Gujarati IndianC;C 55% C;T 37% G;G 0% T;T 8%
  • Luhya (Kenya)C;C 59% C;T 34% G;G 0% T;T 7%
  • Mexican ancestry (Los Angeles)C;C 72% C;T 26% G;G 0% T;T 2%
  • Maasai (Kenya)C;C 67% C;T 29% G;G 0% T;T 5%
  • TuscanC;C 79% C;T 19% G;G 0% T;T 2%

Conditions, medicines and genes

Other GOLM1 SNPs

All GOLM1 SNPs

Notes

From SNPedia

Notes

rs7019241, a SNP in the GOLM1 gene, is associated with reduced risk for Alzheimer's disease in a study of ~1100 Canadian patients. The protective allele appears to be rs10868366(T), giving an odds ratio of 0.54 (CI: 0.38 - 0.75). GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population.

Source and license

Adapted from rs7019241 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.