rs712
A SNP in the KRAS gene on chromosome 12. Its most notable genotype is A;A: common in clinvar
- Gene
- KRAS
- Location
- Chr 1225,209,618 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 47%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs712 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 30%
- European ancestry (Utah)A;A 25%
- Han Chinese (Beijing)A;A 6%
- Japanese (Tokyo)A;A 5%
- Yoruba (Nigeria)A;A 77%
- African ancestry (Southwest US)A;A 44%
- Chinese (Denver)A;A 7%
- Gujarati IndianA;A 16%
- Luhya (Kenya)A;A 66%
- Mexican ancestry (Los Angeles)A;A 25%
- Maasai (Kenya)A;A 47%
- TuscanA;A 13%
Related
Other KRAS SNPs
- rs104894359C;GNoonan syndromeVery important
- rs104894360A;TNoonan syndromeVery important
- rs104894361A;TNoonan syndromeVery important
- rs104894364A;GNoonan syndromeVery important
- rs104894365C;TNoonan syndromeVery important
- rs104894366C;GNoonan syndromeVery important
- rs727503110C;TNoonan syndromeVery important
- rs112445441A;CDrug response to cetuximab and panitumumabImportant
Source and license
Adapted from rs712 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.