rs7133914
A SNP in the LRRK2 gene on chromosome 12. Its most notable genotype is G;G: common in complete genomics
- Gene
- LRRK2
- Location
- Chr 1240,309,109 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 10%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 78%
- European ancestry (Utah)G;G 85%
- Han Chinese (Beijing)G;G 90%
- Japanese (Tokyo)G;G 71%
- Yoruba (Nigeria)G;G 72%
- African ancestry (Southwest US)G;G 73%
- Chinese (Denver)G;G 77%
- Gujarati IndianG;G 89%
- Luhya (Kenya)G;G 79%
- Mexican ancestry (Los Angeles)G;G 79%
- Maasai (Kenya)G;G 66%
- TuscanG;G 83%
Related
Other LRRK2 SNPs
- rs33939927A;CParkinson's disease mutation, adult-onsetVery important
- rs34805604A;GParkinson's disease mutation, adult-onsetVery important
- rs34995376A;GParkinson's disease mutation, adult-onsetVery important
- rs35801418A;GParkinson's disease mutation, adult-onsetVery important
- rs35808389A;GParkinson's disease mutation, adult-onsetVery important
- rs35870237C;TParkinson's disease mutation, adult-onsetVery important
- rs74163686A;CParkinson's disease mutation, adult-onsetVery important
- rs281865052A;GParkinson's disease mutation, adult-onsetVery important
Source and license
Adapted from rs7133914 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.