rs72553883

A SNP in the TNFRSF13B gene on chromosome 17. Its most notable genotype is G;T: Possible: common variable immunodeficiency-2

Gene
TNFRSF13B
Location
Chr 1716,940,415 (GRCh38)
Highest magnitude
3.1Important
Tested on
23andMe, AncestryDNA
Minor allele frequency
<1%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;TMost notableBadPossible: common variable immunodeficiency-2Important · 3.1
  2. G;GGoodcommon in clinvarTypical · 0.0

SNPedia records rs72553883 on the minus strand: (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other TNFRSF13B SNPs

All TNFRSF13B SNPs

Notes

From SNPedia

Notes

G;T

Possible mutation pathogenic for common variable immunodeficiency-2, but penetrance unclear

Source and license

Adapted from rs72553883 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.