rs7495174

A SNP in the OCA2 gene on chromosome 15. Its most notable genotype is A;A: blue/gray eyes more likely

Gene
OCA2
Location
Chr 1528,099,092 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
26%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodblue/gray eyes more likelyTypical · 0.053% of people
  2. A;GNot ratedblue/gray eyes less likelyTypical · 0.032% of people
  3. G;GNot ratedblue/gray eyes less likelyTypical · 0.015% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 53% A;G 32% G;G 15%
  • European ancestry (Utah)A;A 90% A;G 10% G;G 0%
  • Han Chinese (Beijing)A;A 15% A;G 43% G;G 42%
  • Japanese (Tokyo)A;A 14% A;G 40% G;G 46%
  • Yoruba (Nigeria)A;A 71% A;G 26% G;G 3%
  • African ancestry (Southwest US)A;A 72% A;G 26% G;G 2%
  • Chinese (Denver)A;A 9% A;G 45% G;G 46%
  • Gujarati IndianA;A 50% A;G 44% G;G 7%
  • Luhya (Kenya)A;A 61% A;G 35% G;G 5%
  • Mexican ancestry (Los Angeles)A;A 66% A;G 33% G;G 2%
  • Maasai (Kenya)A;A 69% A;G 26% G;G 5%
  • TuscanA;A 71% A;G 26% G;G 4%

Other OCA2 SNPs

All OCA2 SNPs

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

rs7495174 is located in intron 1 of the OCA2 gene. The (A) allele (in dbSNP orientation) is associated with blue or green eye color in Caucasians. . This SNP is 1 of 3 SNPs defining a haplotype that has been studied for association with eye color. The full details on the correspondence between the haplotype and eye color can be found on the OCA2 page.

Source and license

Adapted from rs7495174 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.