rs7743761(A;A)

20x increased risk of Ankylosing Spondylitis.

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
12%Average of 11 populations
On SNPedia
rs7743761(A;A)
Gene
DHFRP2

Frequency

Share of people with A;A in each HapMap population.

  • Mexican ancestry (Los Angeles)19%
  • Japanese (Tokyo)18%
  • Luhya (Kenya)16%
  • Yoruba (Nigeria)15%
  • African ancestry (Southwest US)14%
  • Gujarati Indian11%
  • Chinese (Denver)10%
  • Tuscan9%
  • Maasai (Kenya)8%
  • Han Chinese (Beijing)8%
  • European ancestry (Utah)3%

Other genotypes of rs7743761

  1. A;CBad4.6x increased risk of Ankylosing Spondylitis.Worth knowing · 2.044% of people
  2. C;CGoodNormal (lower) risk of Ankylosing Spondylitis.Minor · 1.945% of people

All about rs7743761

Notes

From SNPedia

Greatly increased odds (but still only about 2%) of this disease. Ankylosing Spondylitis is a rare autoimmune disease that causes inflammation of the spine and joints. The usual age of onset is from the late teens to 40 years of age. Some people with ankylosing spondylitis have onset of symptoms when younger than 16 years. This form of AS is referred to as juvenile-onset ankylosing spondylitis. Reference: http://www.emedicinehealth.com/ankylosing_spondylitis_rheumatologic_perspective/article_em.htm

Source and license

Adapted from rs7743761(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.